Clive and Elsa are superstars of the genetic engineering world. They specialize in splicing together DNA from different animals to create fantastical new hybrids. The charismatic couple wants to use human DNA in a new hybrid – something that could yield astronomical medical benefits. The pharmaceutical company that funds their research, however, is more interested in exploiting their earlier triumphs for easier, short-term profit. Clive and Elsa secretly conduct their own experiment. The result is Dren: an amazing creature who exhibits an array of unexpected developments, both physical and intellectual. Dren exceeds their wildest dreams... and, ultimately, their most terrifying nightmare.

Brad Anderson created the decades-running newspaper comic strip, about a mischievous Great Dane who lives with the Winslow family, in 1954. The big dog then appeared in several animated episodes of "Heathcliff" and "Garfield and Friends."

"Get Him to the Greek" reunites Jonah Hill and Russell Brand with "Forgetting Sarah Marshall" director Nicholas Stoller in the story of a record company intern with two days to drag an uncooperative rock legend to Hollywood for a comeback concert. The comedy is the latest film from producer Judd Apatow ("The 40-Year-Old Virgin," "Knocked Up," "Funny People").
Aaron Green (Hill) gets things done. The ambitious 23-year-old has exaggerated his way into a dream job just in time for a career-making assignment. His mission: Fly to London and escort a rock god to L.A.'s Greek Theatre for the first-stop on a $100-million tour. His warning: Turn your back on him at your own peril.
British rocker Aldous Snow (Brand) is both a brilliant musician and walking sex. Weary of yes men and piles of money, the former front man is searching for the meaning of life. But that doesn't mean he can't have a few orgies while he finds it. When he learns his true love is in California, Aldous makes it his quest...

Spencer Aimes (Ashton Kutcher) is just your average, undercover, government-hired super-assassin accustomed to a life of exotic European locales, flashy sports cars and even flashier women. But when he meets Jen Kornfeldt (Katherine Heigl), a beautiful, fun-loving computer tech recovering from a bad break-up, he finds true love... and happily trades international intrigue for domestic bliss.
Three years later, Spencer and Jen are still enjoying a picture-perfect marriage – that is, until the morning after Spencer's 30th birthday. That's when Spencer and Jen learn he's the target of a multi-million dollar hit. Even worse, the hired killers have been stalking the happy couple for years, and could be anyone: friends, neighbors, the grocery store clerk, even that crabby old guy shuffling across the street.
Now Spencer and Jen are on the run for their lives. As their suburban paradise turns into a paranoid game of dodge-the-bullet, they must find out who wants Spencer dead and why, all th...